What Is The Difference Between CBD And THC

This question is asked a lot and rightly so. Although CBD and THC are similar in some ways, they are also very different.



Both come from the cannabis plant and are made up of the same molecular structure, both are similar to our body’s endocannabinoid system and react to CB1 and CB2 receptors, and both are used in the treatment of medical conditions.


In spite of these similarities, there are noticeable differences.

The cannabis plant is made up of three strains for human consumption – Indica, Sativa and Ruderalis, with the main two being Indica and Sativa.

The Indica, when used for medical marijuana, has a higher ratio of CBD to THC and the Sativa plant has a higher ratio of THC to CBD. The plants themselves are different: The Indica is shorter and bushier with wide leaves while the Sativa is tall and thin, with narrow leaves and more fibre.

Sativa, Indica, ruderalis cannabis plants

Their growing conditions are different as well. The Indica grows faster with a higher yield while the Sativa takes longer to grow and mature and requires more light.

The third strain, the Ruderalis which is not talked about as much, is lower in THC than either of the Sativa or Indica plants and because of this, it is not grown much for recreational use. It is limited in its production of hemp due to its shorter stature. The plants have thin, fibrous stems with little branching and large leaves. It also reaches maturity much quicker than the other two – 5 to 7 weeks from seed.

It was traditionally used in Russian and Mongolian folk medicine for treating depression. Today, it has been crossed with Bedrocan strains (Sativa dominant strain) to produce the Bediol strain (combination of THC and CBD) for patients with medical prescriptions. Because of its higher concentration of CBD, Ruderalis is also used to treat epilepsy, cancer and sclerosis as well as loss of appetite.


The main difference, however, is that CBD will not make you high while THC will. CBD tends to bind more with the CB2 receptors producing a relaxed state while THC tends to bind more with the CB1 receptors producing the ‘high’ or euphoric state.


While both CBD and THC are used to treat medical conditions, it really comes down to what you wish to experience. If you like that feeling of being high, then products containing THC is what you want. However, many people want the pain relief but do not want to experience this high or euphoric state, thus CBD products with little to no THC are better for them.

Some of the various conditions that CBD and THC are used for are:


Seizures associated with Epilepsy*

Pain relief

Anxiety and stress


Mental disorders

As an anti-inflammatory

Increasing appetite

Aiding in smoking or drug withdrawals

Relief from nausea

Migraine headaches

Skin conditions such as acne

Type 1 diabetes

*The FDA (Food and Drug Administration) approved in June 2018, cannabidiol (Epidiolex in an oral solution) to treat two difficult forms of epilepsy – Dravet’s Syndrome and Lennox-Gastaut Syndrome – for patients aged 2 and over. It was the first drug containing a purified marijuana derivative that was approved by the FDA.


Chronic pain


Sleep disorders

Eating disorders

Nausea from cancer treatments

Muscle spasms caused by MS (Multiple Sclerosis)

Crohn’s disease

Muscle relaxant from tremors in Parkinson’s Disease

Irritable Bowel Syndrome (IBS)

PTSD (Post traumatic Stress Disorder)




Dry mouth

Low blood pressure

Prescription drug interference



Changes in appetite and weight


Dry mouth

Dry, red eyes

Increase in appetite/munchies


Memory Impairment


Euphoria (high)

How Ingested or Used

The most common ways both CBD and THC are ingested or used are in the following ways:



Inhalation (vaping)


Topical Creams and salves




Leave a Comment